Trifolium pratense is a perennial flowering herb found throughout the world. The plant has a long history of being thought to bring good luck. In Western herbal medicine, red clover is used to as a skin remedy, especially for managing eczema and skin itchiness. Isoflavones in red clover has been reported to increase collagen production and improve the skin barrier. Biochanin, isolated in red clover extracts has been shown to have skin brightening activity by reducing melanin synthesis. Moreover, polysaccharides from the aerial parts can inhibit nitric oxide production, suggesting anti-inflammatory activity.