Prunella vulgaris has been traditionally used for wounds on the skin and burns. It is also used for drawing out infections, such as abscesses and boils. In Western herbalism, Self-heal has been commonly used as an astringent and demulcent, stabilizing tissue and protecting the skin’s moisture at the same time. Self-heal contains a number of phytochemicals such as rutin, betulinic acid and delphinidin. It is especially high in rosmarinic acid, known to exhibit antioxidant and anti-inflammatory activities. Caffeic acid is known to show significant protective effects, whilst phenolic acids are reported to accelerate wound healing. Many research studies have been conducted identifying Self-heal extract to have antioxidant, antimicrobial and anti-inflammatory activities.